Open J Psychiatry Allied Sci. 2015;6:138-42. doi: 10.5958/2394-2061.2015.00012.9. Epub 2015 May 7.

Clinical study on role of life events in genesis of neurotic disorders and depression. 

Medhi D, Das PD. 

Abstract

This study was conducted to know about the role of life events in genesis of neurotic disorders and depression in four groups of patients with dissociative disorder, somatisation disorder, generalized anxiety disorder (GAD), and depression. It was conducted in the Department of Psychiatry, Gauhati Medical College and Hospital, Guwahati, Assam, India. It was a case control study. Hundred cases of neurotic disorders and depression (25 cases in each group) attending indoor and outdoor, and diagnosed using research diagnostic criteria of the tenth revision of the International Statistical Classification of Diseases and Related Health Problems (ICD-10) were compared with similar number of matched controls, in respect to number, scoring, and type of life events occurring within one year prior to the onset of illness using the Presumptive Stressful Life Events Scale (PSLES). Variables related to socio-demographic characteristics were also seen between cases and controls. Results were analysed using Student’s t test. Number of life events was significantly higher in depressive and generalized anxiety groups than control group. Total life events scores were significantly higher in depressive and generalized anxiety group than control group. Undesirable events were significantly higher in all groups. Personal events were significantly higher in depressives than control. Events related to interpersonal relation were significantly higher in depressive, dissociative, and GAD groups than control. Bereavement was closely associated with depression and GAD. Events related to health, finance, and education were higher in dissociative group than control. Events related to move were found significantly higher in GAD group than control. Implications of the findings are discussed.

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